• Ryanodine receptor and MG

    Posted by Community Member on July 3, 2024 at 5:30 am

    Do you have Myasthenia gravis, and did you test positive for antibodies against ryanodine receptors (RyR)?

     

    “In MG, core symptoms of muscle weakness and fatigue are caused by self-reactive antibodies that attack proteins important for nerve-muscle communication. These antibodies target AChRs in about 85% of cases. Still, other more rare antibody subtypes — such as those targeting RyR or titin — can be found in MG patients, and sometimes multiple antibody types will be present in one person” (https://forumsstg.myastheniagravisnews.com/news/worse-disease-course-antibodies-pediatric-myasthenia-gravis/).

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