Myasthenia Gravis News Community › Forums › Healthcare and Treatments › Seronegative myasthenia gravis: share your experience › Reply To: Seronegative myasthenia gravis: share your experience

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    Being Seronegative has been an extremely challenging experience!!!! Doctors do not believe you have the diagnosis even with a positive single fiber EMG. It took years of getting an incorrect diagnosis prior to me finding a seronegative friendly doctor. I was able to get my thymectomy which helped so very much, however many others are not allowed due to being seronegative. I have CVID, which means I do not make enough IGG, or IGA. I have 6 autoimmune diseases, and I am negative for all because I do not make enough immunoglobulins for the tests to be accurate. Others like me are suffering and we cannot get the approved medications because our blood tests are negative even though we have the disease. More doctors need to be educated in the understanding that clinical testing other than blood tests should be accepted. The FDA needs to adjust the clinical trial inclusion criteria to allow seronegative patients participate in trials so that we can get the medications that we need. It is such a broken process.