Myasthenia Gravis News Community › Forums › Healthcare and Treatments › What dose of Mestinon (Pyridostigmine) and how often has worked well for your body? › Reply To: What dose of Mestinon (Pyridostigmine) and how often has worked well for your body?

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    I was originally prescribed 60 mg of Mestinon 3 times daily. After 6 months, my neurologist started weaning me off steroids and added that I could experiment with weaning off the Mestinon as well. I went down to taking it 2 times daily (morning and night) and after a few days of adjusting, it worked out well. Recently, he suggested that I try tapering it off a little more to help with the extreme sweating I have experienced this summer. So, I tried to take 30 mg 3 times daily but had more muscle weakness and vision issues so I went back to the 60 mg 2 times per day. It is crazy to think that the additional 30 mg made such a big difference for me.