Reply To: What dose of Mestinon (Pyridostigmine) and how often has worked well for your body?

[Community Member]

I began with 60mg pyridostigmine 4x daily 10 months ago; no improvement. Added IVIG every other week; no improvement. Added 250mg mycophenolate 2x daily in January, increased strength of IVIG; continued to decline. Increased mycophenolate to 500mg 2x daily and added 180mg pyridostigmine ER 2x daily and I FINALLY stopped worsening. Now I can no longer get the 180mg ER (manufacturing shortage) and I am backsliding. It’s a shame that I finally found a regimen that offered some slice of “normal” and then lost it.