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The night time severe cramps in my calfs is annoying especially when I have to get up and stretch my legs to make it stop. But, that’s an aggregation. The fatigue is more than an aggravation. It’s making life harder on an everyday basis. But the worst, and it’s getting worse rapidly, is the weakening of the muscles that control the diaphragm. It’s becoming harder and harder to breathe. Now I see why this symptom is the one that kills MG sufferers. It’s killing me I believe.