Myasthenia Gravis News Community › Forums › Healthcare and Treatments › Does anyone have MG with anti-LRP4 antibody and what treatment works › Reply To: Does anyone have MG with anti-LRP4 antibody and what treatment works
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MemberThere is a rare MG anti-LRP4 antibody (low-density lipoprotein receptor-related protein 4) that is the most recent MG antibody to be identified, and there is a special blood test for it besides confirmation with an EMG and single fiber test.. Maybe it was discovered 3 or 4 years ago. Most people with MG have the AChR antibody (85%) and then about 10-13% have the MuSK antibody and about 2-3% have the LRP4 antibody. Some people have a combination of these antibodies but they all cause MG, only some function differently in our neuromuscular communication pathways. The problem for those of us with the rare LRP4 antibody is that we sometimes don’t respond as well to the more common therapies. Most neuromuscular specialists haven’t even treated anyone with this antibody. Thanks for asking.