Reply To: What dose of Mestinon (Pyridostigmine) and how often has worked well for your body?

[Community Member]

4x60mg every 4-5 h. I have had refractory MG for 27 years. Once Rituximab stopped working the dose went from 2 x60 mg every 3 h up to 3×60 mg every 1-3 h when IVIG was cut back before we worked out the Rituximab stopped working and then up to 4 x 60 mg, which gives me the longest gap between doses , as 3 tablets only gets me 3h. Finally some predictability and regularity with Ravulizumab.