Reply To: Neostigmine bromide nasal spray

[Community Member]

Thanks for sharing! You’re on to something: https://pubmed.ncbi.nlm.nih.gov/1573422/ The article mentions no side effects – have you had any? Any nose bleeds?

I take Cellcept regularly but use a Mestinon tablet as needed as a quick pick up for muscle fatigue, especially with swallowing, but I get severe eye twitches from Mestinon. I’ll discuss neostigmine nasal spray as a possible alternative with my neurologist.

pubmed.ncbi.nlm.nih.gov

Efficacy of intranasal administration of neostigmine in myasthenic patients - PubMed

The efficacy of intranasally administered neostigmine was tested in 22 patients with generalized myasthenia gravis (MG). Topical therapy to the highly vascularized oropharynx proved to be quickly effective in 5-15 min both clinically and electrophysiologically. Twenty-eight MG patients were then … Continue reading