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Lots of good input from everyone so thank you! I have been similar to many of you and it has been a journey to figure it out with the tummy issues. Being that I take 180 MG once a day Pyridostigmine (Mestinin generic) and Prednisone (now 5mg once a day on MWF), my nuerologist has me take Omeprazole (Pepcid) 40MG daily which really seems to help. Like someone else mentioned, I start with a greek yogurt and eat something before taking my meds and that has really seemed to help. It can still vary based on what I eat, but an upset stomach is much more rare now if I just eat first and do one of the greek yogurts that is to help the tummy. Good luck and appreciate this community working through it together!