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My Neuro changed me from Solaris to Ultomiris a few months ago. I have noticed a positive effect that seems to take a day or two to kick in. My wife has noticed that I seem to slow down a bit as I get a week or so before my next dosage. Infusions are every 8 weeks and are done in my home. I think I feel more active than I did on Solaris. Not a huge amount but some more active. My experience is obviously positive.