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Michelle Regardless of what the single-fiber EMG test shows it seems clear — as you seem to have concluded — that you should be on prednisone. If a moderate 10mg dose of prednisone helped you as dramatically as you describe it makes no sense that you are suffering on ineffective mestinon.
For your information, I am also positive for AchR blocking antibodies, mestinon does not work for me, and 5mg prednisone does work.
Good luck. It seems a moderate dose of prednisone will help you. I hope so. If your current physician will not help, find a new doctor.
Tom