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At my diagnosis and first hospitalization Plasmapheresis was utilized along with Mestinon and Prednisone. After a week in the hospital I was discharged only to be readmitted approximately two weeks later. Again Plasmapheresis was used and after a week discharged. The same thing again. Two to three weeks and back in the hospital. My doctors apparently love Plasmapheresis for they tried it for a third time. After that failed I guess someone got that was not going to work.( the definition of insanity is doing the same thing again and again and expecting a different result). I was given a 5 day course of IVIG and discharged with orders for biweekly infusions of IVIG. I was on IVIG for only 6 weeks before changing to Soliris. I had no side effects from the infusion of IVIG. I did suffer from great deal of fatigue during the course of taking IVIG but cannot say for sure if it was due to the IVIG or just being in and out of the hospital over the course of three months. At least from me Plasmapheresis was a near worthless therapy that only delayed the proper therapy from being implemented.