Reply To: Mestinon 60 mg verses Mestinon XR 180 mg

[Community Member]

I tried pyridostigmine ER for 3 days, and it didn’t work for me. I had a bad incident of not swallowing.

My guess as to what happened is that the extended release never reached some threshold level of pyridostigmine in my blood. I’m back to taking the regular drug 3, sometimes 4, times per day and am doing well.