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Last year I started Mestinon and also concurrently started getting leg cramps. I didn’t realize that they might be related until I read your message. I get them at night in bed usually before falling asleep. I can also initiate them by extending or flexing my foot, and surprisingly my toes, too. I’ve been trying Magnesium pills for a couple of months (they are supposed to relieve muscle cramps, I’ve been informed) but no relief so far. I’m interested to see other responses to your question. Thanks!
Mike