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I didn’t consider low pressure as I don’t live in a high altitude; however, I cannot fly b/c they don’t pressurize the planes well enough. I found out the hard way on a short flight (Orlando to Richmond VA). I was hard to arouse when we were near Richmond (my husband just though I fell asleep)— I was having problems breathing. Fortunately I had my Trilogy as a carry-on-he got it, I put it on, and by the time it was time for us to “de-plane” (last b/c of my wheelchair) I was feeling much bettter and could take the trilogy off.