I had a port put in and had no problems with it.  After about a year or so they decided to take it out.  I don’t recall why it was removed.  It was put in because I was considered such a “hard stick” when it came time to get infusions.  I now get IVIG and Ultomiris infusions and only rarely have serious problems getting “stuck” now.  I do drink more water before infusions than I used to.